diff --git a/src/components/Form/src/hooks/useLabelWidth.ts b/src/components/Form/src/hooks/useLabelWidth.ts
index 7fcc021e600cae89f73417dc11e6166a57dabdc2..37948351058ca314efcbfda8cb1b1a443d232435 100644
--- a/src/components/Form/src/hooks/useLabelWidth.ts
+++ b/src/components/Form/src/hooks/useLabelWidth.ts
@@ -10,7 +10,7 @@ export function useItemLabelWidth(schemaItemRef: Ref<FormSchema>, propsRef: Ref<
     const { labelCol = {}, wrapperCol = {} } = schemaItem.itemProps || {};
     const { labelWidth, disabledLabelWidth } = schemaItem;
 
-    const { labelWidth: globalLabelWidth, labelCol: globalLabelCol, wrapperCol: globWrapperCol } = unref(propsRef);
+    const { labelWidth: globalLabelWidth, labelCol: globalLabelCol, wrapperCol: globWrapperCol, layout } = unref(propsRef);
 
     // update-begin--author:sunjianlei---date:20211104---for: 禁用全局 labelWidth，不自动设置 textAlign --------
     if (disabledLabelWidth) {
@@ -35,7 +35,10 @@ export function useItemLabelWidth(schemaItemRef: Ref<FormSchema>, propsRef: Ref<
 
     return {
       labelCol: { style: { width }, ...col },
-      wrapperCol: { style: { width: `calc(100% - ${width})` }, ...wrapCol },
+      wrapperCol: {
+        style: { width: layout === 'vertical' ? '100%' : `calc(100% - ${width})` },
+        ...wrapCol,
+      },
     };
   });
 }